GAF® (Glyoxal Acid Free) – Formalin Free Fixative

Every day in Europe, around 1,000,000 healthcare workers are exposed to carcinogenic formalin vapors, and the resulting five times higher than average risk of developing occupational diseases (respiratory tract cancer, asthma, allergies) as well as cognitive dysfunction.

Formalin, in fact, is an aqueous solution based on formaldehyde. Formaldehyde is a substance classified by the EU as carcinogenic and mutagenic (like asbestos), and its use has been strictly limited by EU Regulation ((EU) 2014/895, (EU) 2018/675, EU 2019/983).

However, in the absence of a technically viable and safe alternative, formalin is still currently the most widely used standard fixative in Pathological Anatomy, for tissue fixation. Addax Biosciences has developed, patented, and validated GAF®, an innovative histological, non-carcinogenic fixative, capable of offering the same tissue fixation performance and diagnostic accuracy, over the full range of application as formalin.